Location: San Diego, CA or Remote

Position Description: Empirico, an early-stage biotechnology company, is looking for a Lead Data Engineer that is motivated by the opportunity to develop high performance distributed data systems that allow us to analyze massive and complex biological datasets.  You will work closely with scientists and engineers that have a passion for building out novel systems and analytical approaches toward the treatment and prevention of disease.

Responsibilities:

Your responsibilities will focus on the design, implementation, and deployment of modern distributed data systems and pipelines.  You will be expected to:

• Be a domain expert in the area of distributed data systems
• Collaborate closely with an interdisciplinary team of scientists and engineers to design, develop, deploy, and support scalable data systems and pipelines.
• Take lead on complex data-related problems around the modeling, processing, and analysis of the largest genetic and phenotypic datasets available
• Take a leading role in identifying and resolving performance bottlenecks and pain points throughout our data infrastructure
• Enhance and support our data platform as it scales

Requirements:

• 5+ years of industry experience building distributed data systems
• Strong technical skillset that spans a broad range of technologies, programming languages, and paradigms
• Expert with Apache Spark or similar distributed frameworks and technologies
• Proficient with multiple programming languages (preferably Scala, Python, and/or Java)
• Experience processing, modeling, and analyzing large and heterogenous datasets
• Demonstrated ability for writing robust, readable, and testable code
• An interest in learning about the intersection of software engineering, genetics, and drug discovery
• Applicants must have authorization to work in the United States

Empirico is a venture-backed, next-generation therapeutics company founded on utilizing huge biological datasets, human genetics and programmable biology to power novel target discovery and development. Empirico’s Precision Insights Platform was purpose-built for therapeutic discovery and leverages a world-leading dataset and advanced algorithmic approaches to identify and prioritize therapeutic targets with a high probability of translational success. High priority therapeutic targets are experimentally validated in-house prior to progressing through pre-clinical development with the most optimal therapeutic modality. Empirico is headquartered in San Diego, CA with laboratories in Madison, WI.

To all agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Location: San Diego, CA or Remote

Position Description: Empirico, an early-stage biotechnology company, is looking for a talented data engineer that is motivated by the opportunity to develop cutting edge data architectures, models, and analyses that allow our scientists to discover new medicines.  You will work closely with scientists and engineers that have a passion for building out novel systems and analytical approaches toward the treatment and prevention of disease.

Responsibilities:

Your responsibilities will focus on the design, implementation, and deployment of modern data infrastructure, models, analyses, and pipelines.  You will be expected to:

• Collaborate closely with an interdisciplinary team of scientists and engineers to design, develop, deploy, and support scalable data pipelines.
• Take on complex data-related problems around the modeling and analysis of the largest genetic and phenotypic datasets available
• Identify and resolve performance bottlenecks and pain points throughout our data infrastructure
• Enhance and support our data platform as it scales

Requirements:

• B.S., M.S., Ph.D. in computer science, engineering, mathematics, or equivalent industry experience
• Strong technical skillset that spans a broad range of technologies, programming languages, and paradigms
• Proficient with multiple programming languages (preferably Scala, Python, and/or Java)
• Experience processing, modeling, and analyzing large and heterogenous datasets
• Demonstrated ability for writing robust, readable, and testable code
• Experience with AWS, Spark and working in a distributed system setting is a plus
• An interest in learning about the intersection of software engineering, genetics, and drug discovery
• Applicants must have authorization to work in the United States

Empirico is a venture-backed, next-generation therapeutics company founded on utilizing huge biological datasets, human genetics and programmable biology to power novel target discovery and development. Empirico’s Precision Insights Platform was purpose-built for therapeutic discovery and leverages a world-leading dataset and advanced algorithmic approaches to identify and prioritize therapeutic targets with a high probability of translational success. High priority therapeutic targets are experimentally validated in-house prior to progressing through pre-clinical development with the most optimal therapeutic modality. Empirico is headquartered in San Diego, CA with laboratories in Madison, WI.

To all agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Location: San Diego, CA

Position Description: Empirico, an early-stage biotechnology company, is looking for a talented software engineer that is motivated by the opportunity to build scalable data systems that power the discovery of new medicines.  You will work closely with a team of engineers and computational scientists to build and extend Empirico’s data infrastructure, which include cloud-based systems and services that operate on some of the largest biological datasets in the world.

Responsibilities:

Your responsibilities will focus around designing and implementing robust and extensible data systems.  You will be expected to:

• Design and implement scalable data infrastructure and pipelines
• Implement scalable algorithms in a distributed systems setting
• Collaborate closely with an interdisciplinary team of scientists and engineers to address system pain points
• Improve developer efficiency and system quality through emphasis on elegant code
• Advocate for systems and engineering practice improvements

Requirements:

• 2+ years professional experience designing and developing software on modern distributed data systems
• Experience processing and analyzing large and heterogeneous datasets
• Strong technical skillset that spans a broad range of technologies, programming languages, and paradigms
• Passionate about systems thinking and drive towards elegant and automated solutions to data problems
• Experience with Spark and Scala or other functional programming language is a plus
• Applicants must have authorization to work in the United States

Empirico is a venture-backed, next-generation therapeutics company founded on utilizing huge biological datasets, human genetics and programmable biology to power novel target discovery and development. Empirico’s Precision Insights Platform was purpose-built for therapeutic discovery and leverages a world-leading dataset and advanced algorithmic approaches to identify and prioritize therapeutic targets with a high probability of translational success. High priority therapeutic targets are experimentally validated in-house prior to progressing through pre-clinical development with the most optimal therapeutic modality. Empirico is headquartered in San Diego, CA with laboratories in Madison, WI.

To all agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Location:  Madison, WI

Position Description: Empirico, an early-stage biotechnology company, is looking for a senior scientist-level chemist experienced in solid phase oligonucleotide synthesis, and analytics. This is an excellent opportunity for a highly motivated, creative scientist to be a vital member of our Development team.

Responsibilities:

• Perform synthesis, purification, and analysis of oligonucleotides
• Take part in sequence optimization design
• Develop oligonucleotide analytics to transfer to CMOs and CROs
• Perform bioconjugation, purification, and characterization of oligonucleotide conjugates
• Maintain and improve an internal database for managing and tracking oligonucleotides
• Present research findings in a multi-disciplinary environment
• Potential to train and supervise future oligonucleotide chemistry hires

Requirements:

• MS or PhD in Organic chemistry with 2-4 years of solid phase oligonucleotide synthesis experience.
• Demonstrated experience managing an oligonucleotide synthesis lab is a must
• GLP experience developing oligonucleotide purity, identity and duplex % assays for transfer to CMOs
• Demonstrated ability to design, and interpret sequence design results in order to produce highly potent SiRNAs
• Experienced in the synthesis, purification, and analysis of siRNA conjugates
• Experienced in developing HPLC, LCMS, and MALDI methods for analysis of oligonucleotides
• Desire to work in a fast-paced and dynamic startup environment
• Applicants must have authorization to work in the U.S.

Empirico is a venture-backed, next-generation therapeutics company founded on utilizing huge biological datasets, human genetics and programmable biology to power novel target discovery and development. Empirico’s Precision Insights Platform was purpose-built for therapeutic discovery and leverages a world-leading dataset and advanced algorithmic approaches to identify and prioritize therapeutic targets with a high probability of translational success. High priority therapeutic targets are experimentally validated in-house prior to progressing through pre-clinical development with the most optimal therapeutic modality. Empirico is headquartered in San Diego, CA with laboratories in Madison, WI.

To all agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Location: Madison, WI

Position Description: Empirico, an early-stage biotechnology company, is looking for a talented scientist to join our Development team to help advance our growing pipeline. This position offers a unique opportunity to participate and support multiple projects across different stages of preclinical development in multiple therapeutic areas. You will work closely with other scientists that have a passion for finding novel approaches toward the treatment and prevention of disease.

Responsibilities:

Your responsibilities will include the validation of potential new targets, aiding in drug discovery efforts, as well as establishing pharmacological readouts for pipeline candidates. You will be expected to:

• Develop and conduct in vitro biochemical and cell-based assays with cell lines, primary cells, and animal tissue and blood samples
• Design and perform new and existing assays based on project requirements in collaboration with the scientific team, accurately document findings, analyze data and communicate key scientific data internally
• Work with outside vendors and partners to establish assays that advance project goals
• Stay up to date on scientific literature and technical advances in relevant fields
• Be a team player who enjoys an open environment where you can contribute in highly meaningful and impactful ways

Requirements:

• PhD in biochemistry, cell biology, genetics, pharmacology, or related field
• 2+ years Post-PhD experience (Postdoc or Industry) is a plus

• Experience with mammalian cell culture (primary cell culture experience preferred)
• Advanced knowledge of cellular and molecular biology techniques (qRT-PCR, cell-based assays, Western blot, immunoassays – ELISA, AlphaLISA, Luminex, etc.)

• Desire to work in a fast-paced and dynamic startup environment
• Applicants must have authorization to work in the U.S.

Empirico is a venture-backed, next-generation therapeutics company founded on utilizing huge biological datasets, human genetics and programmable biology to power novel target discovery and development. Empirico’s Precision Insights Platform was purpose-built for therapeutic discovery and leverages a world-leading dataset and advanced algorithmic approaches to identify and prioritize therapeutic targets with a high probability of translational success. High priority therapeutic targets are experimentally validated in-house prior to progressing through pre-clinical development with the most optimal therapeutic modality. Empirico is headquartered in San Diego, CA with laboratories in Madison, WI.

To all agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Location:  San Diego, CA

Position Description: Empirico, an early-stage biotechnology company, is looking for a talented bioinformatics engineer with data science skills who is interested in analyzing large scale human genetics data for the purpose of therapeutic target discovery.

Responsibilities:

Your responsibilities will primarily consist of performing analyses and building robust computational pipelines and tools critical to Empirico’s drug discovery efforts. You will be expected to:

• Collaborate closely with a multidisciplinary team consisting of human geneticists, bioinformatics scientists and software engineers, using your computational skills to gain insights from massive genetic datasets
• Design, develop and deploy robust data analysis pipelines and software tools to support target discovery
• Help implement cutting-edge bioinformatics methods and algorithms (such as those described in the literature) to advance Empirico’s discovery initiatives
• Integrate and analyze large, complex data sets to extract information useful to our target discovery platforms
• Perform focused genetic analyses to gain insights into novel target biology and clearly communicate these analyses to Empirico colleagues
• Perform analyses to address platform/application QC

Requirements:

• This position requires a BS or MS in bioinformatics or a related discipline (eg computer science, mathematics) with 0-3 years of experience.
• Proficient in at least one programming language (preferably Python, or Scala)
• Familiarity with Linux command-line based tools and bash scripting
• Experience using HPC/cloud computing environments (AWS, Azure, GCP) is a plus
• Hands on experience processing, analyzing, and visualizing datasets
• Familiarity with use of version control systems such as Git
• A firm understanding of applied statistical methods; knowledge of the principles of statistical genetics is a plus
• Demonstrated ability for writing readable, testable, and SOLID code
• An ideal candidate is self-motivated, and can learn and work independently
• Applicants must have authorization to work in the U.S.

Empirico is a venture-backed, next-generation therapeutics company founded on utilizing huge biological datasets, human genetics and programmable biology to power novel target discovery and development. Empirico’s Precision Insights Platform was purpose-built for therapeutic discovery and leverages a world-leading dataset and advanced algorithmic approaches to identify and prioritize therapeutic targets with a high probability of translational success. High priority therapeutic targets are experimentally validated in-house prior to progressing through pre-clinical development with the most optimal therapeutic modality. Empirico is headquartered in San Diego, CA with laboratories in Madison, WI.

To all agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Position Title: Laboratory Assistant (Temporary, Part-Time)

Location: Madison, WI

Position Description: Empirico, a human genetics-focused biotechnology company, is looking for a laboratory assistant to help with routine laboratory operations. This is an excellent opportunity to gain hands-on experience working at a highly innovative biotechnology company and with experienced scientists that have a passion for finding novel approaches toward the treatment and prevention of disease. This is a part-time, temporary position and you will typically be asked to work approximately 10-15 hours per week.

Responsibilities:

Your responsibilities will include:

• Ordering of reagents/supplies
• Shipping and receiving packages
• Inventory management
• Filing and organization of MSDS forms
• General laboratory housekeeping including dishwashing, autoclaving, and waste removal
• You will also have the opportunity to perform routine laboratory assays and reagent preparation and to receive training in these techniques, if required

Requirements:

• High School diploma or equivalent (B.S in molecular biology or related field is a plus)
• Previous experience working in a laboratory environment (experience performing routine laboratory assays and reagent preparation is a plus)
• Applicants must have authorization to work in the U.S.

Empirico is a venture-backed, next-generation therapeutics company founded on utilizing huge biological datasets, human genetics and programmable biology to power novel target discovery and development. Empirico is headquartered in San Diego, CA with laboratories in Madison, WI.

Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

To all agencies: Please do not contact any employee of Empirico about this position.

Position Title: Data Engineer

Location: San Diego, CA

Position Description: Empirico, an early-stage biotechnology company, is looking for a talented data engineer that is motivated by the opportunity to develop cutting edge data architectures that allow our scientists to discover new medicines.  You will work closely with scientists and engineers that have a passion for building out novel systems and approaches toward the treatment and prevention of disease.

Responsibilities:

Your responsibilities will focus around the design, implementation, and deployment of modern data infrastructure, methods, pipelines, and applications.  You will be expected to:

• Collaborate closely with an interdisciplinary team of scientists and engineers to design, develop, and deploy robust data pipelines that analyze huge biological datasets.
• Take on complex data-related problems using the largest genetic and phenotypic datasets available
• Identify and resolve performance bottlenecks and pain points throughout our data infrastructure
• Enhance and support our platform as it scales

Requirements:

• S, M.S, Ph.D. in computer science, engineering, mathematics, or equivalent industry experience
• Strong technical skillset that spans a broad range of technologies, programming languages, and paradigms
• Proficient with multiple programming languages (preferably Scala, Python, and/or Java)
• Experience processing, modeling, and analyzing large and heterogenous datasets
• Experience with distributed data processing technologies (Spark, Hadoop, etc.)
• Familiarity with cloud computing (AWS, Azure, or GCP)
• Experience and familiarity with genetic, clinical, and phenotypic data, including standard formats a plus
• Demonstrated ability for writing readable, testable, and SOLID code

Empirico is a venture-backed, next-generation therapeutics company founded on utilizing huge biological datasets, human genetics and programmable biology to power novel target discovery and development. Empirico’s Precision Insights Platform was purpose-built for therapeutic discovery and leverages a world-leading dataset and advanced algorithmic approaches to identify and prioritize therapeutic targets with a high probability of translational success. High priority therapeutic targets are experimentally validated in-house prior to progressing through pre-clinical development with the most optimal therapeutic modality. Empirico is headquartered in San Diego, CA with laboratories in Madison, WI.

To all agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Location: San Diego, CA

Position Description: Empirico, an early-stage biotechnology company, is looking for a Program and Alliance Manager to provide operational leadership across a number of early-stage therapeutic programs and collaborations with external parties. This is an excellent opportunity for a highly-motivated, creative and organized scientist to be a vital member of a team of experts dedicated to identifying new disease targets and translating those insights into therapeutic programs.

Responsibilities:

Your responsibilities will include monitoring and driving the execution of program and collaboration goals and deliverables. You will be expected to:

• Collaboratively develop, track and manage project plans for internal programs
• Coordinate project tasks and deliverables across internal teams and external service providers
• Contribute to resource planning, financial and capacity assessments
• Organize and lead internal and external meetings including agenda, materials and action items
• Manage and track interactions and deliverables with external partners and collaborators
• Regularly communicate accurate project progress
• Anticipate potential risks or delays, act to minimize them and develop backup strategies
• Identify opportunities for process improvements and collaborate to implement them

Requirements:

• This position requires a MS or PhD in life sciences with experience in program management in the biotech/pharmaceutical industry
• Familiarity with the process, language and tools of drug discovery and development
• Excellent written, verbal and interpersonal communication skills
• Exceptional organizational and time management skills and the ability to multi-task several projects at once
• Proficiency in Excel, PowerPoint, Word and project management tools
• Applicants must have authorization to work in the U.S.

Empirico is a venture-backed, next-generation therapeutics company founded on utilizing huge biological datasets, human genetics and programmable biology to power novel target discovery and development. Empirico’s Precision Insights Platform™ was purpose-built for therapeutic discovery and leverages a world-leading dataset and advanced algorithmic approaches to identify and prioritize therapeutic targets with a high probability of translational success. High priority therapeutic targets are experimentally validated in-house prior to progressing through pre-clinical development with the most optimal therapeutic modality. Empirico is headquartered in San Diego, CA with laboratories in Madison, WI.

To all agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Location: San Diego, CA

Position Description: Empirico, an early-stage biotechnology company, is looking for a talented software engineer that is motivated by the opportunity to build scalable data systems and applications that power the discovery of new medicines.  You will work closely with a team of engineers and scientists to build and extend Empirico’s internal data platform, which include cloud-based systems, services, and web applications that help our scientists discover drug targets from some of the largest biological datasets in the world.

Responsibilities:

Your responsibilities will focus around extending and improving software systems throughout our stack:

• Collaborate with a team of scientists and engineers to design, implement, and enhance applications, services, and infrastructure that are critical to our scientific workflow
• Implement scalable algorithms in a distributed systems setting
• Identify and solve problems across our entire technology stack
• Take ownership of the code and subsystems that you work on
• Uphold a high standard of code quality, systems architecture, and testing

Requirements:

• Proven track record of relevant software and data science projects
• An interest in learning about the intersection of software engineering, genetics, and drug discovery
• Strong technical skillset that spans a broad range of technologies, programming languages, and paradigms
• Sound knowledge of software design and architecture
• Life-science and statistical analysis experience a plus, but not required
• Experience with AWS, Spark and Scala or other functional programming language is a plus
• Applicants must have authorization to work in the United States

Empirico is a venture-backed, next-generation therapeutics company founded on utilizing huge biological datasets, human genetics and programmable biology to power novel target discovery and development. Empirico’s Precision Insights Platform was purpose-built for therapeutic discovery and leverages a world-leading dataset and advanced algorithmic approaches to identify and prioritize therapeutic targets with a high probability of translational success. High priority therapeutic targets are experimentally validated in-house prior to progressing through pre-clinical development with the most optimal therapeutic modality. Empirico is headquartered in San Diego, CA with laboratories in Madison, WI.

To all agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Location: San Diego, CA or Remote

Position Description: Empirico, an early-stage biotechnology company, is looking for a talented software engineer that is motivated by the opportunity to design and build systems that make our data-driven methods of discovering new medicines more efficient.  This role requires close collaboration with a team of engineers and computational scientists working on large-scale, cloud-based infrastructure.

Responsibilities:

Your responsibilities will focus around designing and implementing robust and extensible infrastructure that supports critical engineering and scientific processes.  You will be expected to:

• Spearhead the design and implementation of systems and tools that accelerate the development, testing, and deployment of mission critical infrastructure, applications, and workflows.
• Integrate and take ownership of a modernized operations toolchain
• Collaborate closely with an interdisciplinary team of scientists and engineers to address system pain points
• Integrate metrics systems that allow us to monitor and make data driven decisions to improve platform performance
• Advocate for systems and engineering practice improvements

Requirements:

• 3+ years designing and developing modern infrastructure systems and tools
• Experience operating and maintaining large distributed systems
• Strong technical skillset that spans a broad range of technologies, programming languages, and paradigms
• Passionate about systems thinking and drive towards elegant and automated solutions to operational problems
• Must be able to provide links to relevant open source code, contributions, or publications
• Applicants must have authorization to work in the U.S.

Empirico is a venture-backed, next-generation therapeutics company founded on utilizing huge biological datasets, human genetics and programmable biology to power novel target discovery and development. Empirico’s Precision Insights Platform™ was purpose-built for therapeutic discovery and leverages a world-leading dataset and advanced algorithmic approaches to identify and prioritize therapeutic targets with a high probability of translational success. High priority therapeutic targets are experimentally validated in-house prior to progressing through pre-clinical development with the most optimal therapeutic modality. Empirico is headquartered in San Diego, CA with laboratories in Madison, WI.

To all agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Location: Madison, WI

Position Description: Empirico, an early-stage biotechnology company, is looking for an assistant scientist with a strong background in performing mammalian tissue culture and cell-based assays for the purposes of understanding gene function. This is an excellent opportunity for an experienced scientist that desires to make meaningful contributions in the discovery and validation of new therapeutic targets. You will work closely with other scientists that have a passion for finding novel approaches toward the treatment and prevention of disease.

Responsibilities:

Your responsibilities will include establishing and performing a wide variety of cell-based and molecular biological assays designed to provide insights into gene function. The ideal candidate will also have extensive experience in quantitative protein-based and nucleic acid-based detection systems, be highly organized, and enjoys working in a team environment. You will be expected to:

• Perform a wide variety of cell-based assays
• Aid in the creation of experimental protocols and SOPs
• Maintain detailed experimental records
• Analyze and communicate experimental results
• Perform general laboratory duties including the ordering of reagents/supplies
• Be a team player who enjoys an open environment where you can contribute in highly meaningful and impactful ways

Requirements:

• B.S in molecular biology, biochemistry or related field with 2+ years of experience in a laboratory setting
• Hands on experience using and manipulating mammalian tissue culture systems
• Working knowledge of reporter gene systems, ELISA, AlphaLISA, RT-qPCR, gel electrophoresis
• Proficient in MS Word, Excel and PowerPoint
• Experience in advanced cell culture systems (e.g. air-liquid interface) is a plus
• Previous industry experience is preferred
• Applicants must have authorization to work in the U.S.

Empirico is a venture-backed, next-generation therapeutics company founded on utilizing huge biological datasets, human genetics and programmable biology to power novel target discovery and development. Empirico’s Precision Insights Platform™ was purpose-built for therapeutic discovery and leverages a world-leading dataset and advanced algorithmic approaches to identify and prioritize therapeutic targets with a high probability of translational success. High priority therapeutic targets are experimentally validated in-house prior to progressing through pre-clinical development with the most optimal therapeutic modality. Empirico is headquartered in San Diego, CA with laboratories in Madison, WI.

To all agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Location: Madison, WI

Position Description: Empirico, an early-stage biotechnology company, is looking for an assistant scientist with a strong background in performing biomarker assays. This is an excellent opportunity for an experienced scientist that desires to make meaningful contributions in the discovery and validation of new therapeutic targets. You will work closely with other scientists that have a passion for finding novel approaches toward the treatment and prevention of disease.

Responsibilities:

Your responsibilities will include establishing and performing a wide variety of biochemical and molecular biological assays designed to provide insights into gene function in in vitro and cell culture models. The ideal candidate will have extensive experience in both protein-based and nucleic acid-based assay systems, be highly organized, and enjoys working in a team environment. You will be expected to:

• Perform a wide variety of biomarker assays
• Aid in the creation of experimental protocols and SOPs
• Maintain detailed experimental records
• Analyze and communicate experimental results
• Perform general laboratory duties including the ordering of reagents/supplies
• Be a team player who enjoys an open environment where you can contribute in highly meaningful and impactful ways

Requirements:

• B.S. in molecular biology, biochemistry or related field with 2+ years of experience in a laboratory setting
• Hands on experience of assay systems including ELISA, AlphaLISA, RT-qPCR, reporter gene systems, Luminex
• Proficient in MS Word, Excel and Powerpoint
• Experience in cell culture techniques is a plus
• Previous industry experience is preferred
• Applicants must have authorization to work in the U.S.

Empirico is a venture-backed, next-generation therapeutics company founded on utilizing huge biological datasets, human genetics and programmable biology to power novel target discovery and development. Empirico’s Precision Insights Platform™ was purpose-built for therapeutic discovery and leverages a world-leading dataset and advanced algorithmic approaches to identify and prioritize therapeutic targets with a high probability of translational success. High priority therapeutic targets are experimentally validated in-house prior to progressing through pre-clinical development with the most optimal therapeutic modality. Empirico is headquartered in San Diego, CA with laboratories in Madison, WI.

To all agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Location:  San Diego, CA

Position Description: Empirico, an early-stage biotechnology company, is looking for a scientist-level computational geneticist experienced in analyzing and interpreting large scale human genetics data for the purpose of therapeutic target discovery. This is an excellent opportunity for a highly-motivated, creative scientist to be a vital member of a team of experts dedicated to identifying new disease targets and translating those insights into therapeutic programs.

Responsibilities:

Your responsibilities will include using human genetics data to identify new therapeutic targets in order to advance Empirico’s drug discovery and development pipeline. You will be expected to:

• Work with a multidisciplinary team consisting of human geneticists, bioinformaticians and software engineers to lead the design, execution, and interpretation of in silico human genetic studies
• Discover novel genetic associations with human diseases using Empirico’s world-leading target discovery platform
• Provide genetic intelligence on therapeutic targets of interest for external collaborators
• Create and deliver expert-level presentations that clearly communicate genetic discoveries and stories to colleagues, collaborators and investors
• Translate findings from genetic studies into therapeutic hypotheses and contribute to decisions around therapeutic modality and targeting strategies
• Collaborate with biologists and chemists on the design of in vitro and in vivo experiments to validate therapeutic hypotheses that are motivated by human genetics findings
• Provide novel ideas and critical thinking for the continued development and improvement of Empirico’s target discovery platform
• Survey the latest developments in the broader genetics community and incorporate relevant approaches and findings into internal studies

Requirements:

• This position requires an MD or PhD with 0-3 years of postgraduate experience in human genetics research with a translational focus. Recent graduates and postdocs encouraged to apply.
• Core background MUST be in computational genetics; this position is NOT for scientists with a primarily wet-lab background
• A firm understanding of the principles of statistical genetics and genetic epidemiology
• Demonstrated ability to design, lead and interpret human genetics studies and to discern therapeutic hypotheses
• Familiarity with the design of functional studies to understand the mechanistic basis for genetic associations
• Applicants must have authorization to work in the U.S.

Empirico is a venture-backed, next-generation therapeutics company founded on utilizing huge biological datasets, human genetics and programmable biology to power novel target discovery and development. Empirico’s Precision Insights Platform™ was purpose-built for therapeutic discovery and leverages a world-leading dataset and advanced algorithmic approaches to identify and prioritize therapeutic targets with a high probability of translational success. High priority therapeutic targets are experimentally validated in-house prior to progressing through pre-clinical development with the most optimal therapeutic modality. Empirico is headquartered in San Diego, CA with laboratories in Madison, WI.

To all agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Location:  San Diego, CA

Position Description: Empirico, an early-stage biotechnology company, is looking for a director-level computational geneticist experienced in analyzing and interpreting large scale human genetics data for the purpose of therapeutic target discovery. This is an excellent opportunity for a highly-motivated, creative scientist to be a vital member of a team of experts dedicated to identifying new disease targets and translating those insights into therapeutic programs.

Responsibilities:

Your responsibilities will include using human genetics data to identify new therapeutic targets in order to advance Empirico’s drug discovery and development pipeline. You will be expected to:

• Work with a multidisciplinary team consisting of human geneticists, bioinformaticians and software engineers to lead the design, execution, and interpretation of in silico human genetic studies
• Discover novel genetic associations with human diseases using Empirico’s world-leading target discovery platform
• Provide genetic intelligence on therapeutic targets of interest for external collaborators
• Create and deliver expert-level presentations that clearly communicate genetic discoveries and stories to colleagues, collaborators and investors
• Translate findings from genetic studies into therapeutic hypotheses and contribute to decisions around therapeutic modality and targeting strategies
• Collaborate with biologists and chemists on the design of in vitro and in vivo experiments to validate therapeutic hypotheses that are motivated by human genetics findings
• Provide novel ideas and critical thinking for the continued development and improvement of Empirico’s target discovery platform
• Survey the latest developments in the broader genetics community and incorporate relevant approaches and findings into internal studies

Requirements:

• This position requires an MD or PhD with at least 4-6 years of postgraduate experience in human genetics research with a translational focus. Pay and title commensurate with experience
• Core background MUST be in computational genetics; this position is NOT for scientists with a primarily wet-lab background
• A firm understanding of the principles of statistical genetics and genetic epidemiology
• Demonstrated ability to design, lead and interpret human genetics studies and to discern therapeutic hypotheses
• Familiarity with the design of functional studies to understand the mechanistic basis for genetic associations
• Applicants must have authorization to work in the U.S.

Empirico is a venture-backed, next-generation therapeutics company founded on utilizing huge biological datasets, human genetics and programmable biology to power novel target discovery and development. Empirico’s Precision Insights Platform™ was purpose-built for therapeutic discovery and leverages a world-leading dataset and advanced algorithmic approaches to identify and prioritize therapeutic targets with a high probability of translational success. High priority therapeutic targets are experimentally validated in-house prior to progressing through pre-clinical development with the most optimal therapeutic modality. Empirico is headquartered in San Diego, CA with laboratories in Madison, WI.

To all agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.