Press Releases and Articles


Contact: Jessica Yingling
media@empiricotx.com

Press Releases and Articles

Mon Oct 14

Lead Engineer – Engineering Operations

Location: San Diego, CA or Remote

Position Description: Empirico, an early-stage biotechnology company, is looking for a talented software engineer that is motivated by the opportunity to design and build systems that make our data-driven methods of discovering new medicines more efficient.  This role requires close collaboration with a team of engineers and computational scientists working on large-scale, cloud-based infrastructure.

Responsibilities:

Your responsibilities will focus around designing and implementing robust and extensible infrastructure that supports critical engineering and scientific processes.  You will be expected to:

  • Spearhead the design and implementation of systems and tools that accelerate the development, testing, and deployment of mission critical infrastructure, applications, and workflows.
  • Integrate and take ownership of a modernized operations toolchain
  • Collaborate closely with an interdisciplinary team of scientists and engineers to address system pain points
  • Integrate metrics systems that allow us to monitor and make data driven decisions to improve platform performance
  • Advocate for systems and engineering practice improvements

Requirements:

  • 3+ years designing and developing modern infrastructure systems and tools
  • Experience operating and maintaining large distributed systems
  • Strong technical skillset that spans a broad range of technologies, programming languages, and paradigms
  • Passionate about systems thinking and drive towards elegant and automated solutions to operational problems
  • Must be able to provide links to relevant open source code, contributions, or publications
  • Applicants must have authorization to work in the U.S.

Empirico is a venture-backed, next-generation therapeutics company founded on utilizing huge biological datasets, human genetics and programmable biology to power novel target discovery and development. Empirico’s Precision Insights Platform™ was purpose-built for therapeutic discovery and leverages a world-leading dataset and advanced algorithmic approaches to identify and prioritize therapeutic targets with a high probability of translational success. High priority therapeutic targets are experimentally validated in-house prior to progressing through pre-clinical development with the most optimal therapeutic modality. Empirico is headquartered in San Diego, CA with laboratories in Madison, WI.

To all agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

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Fri Jun 7

Assistant Scientist – In Vitro Validation

Location: Madison, WI

Position Description: Empirico, an early-stage biotechnology company, is looking for an assistant scientist with a strong background in performing mammalian tissue culture and cell-based assays for the purposes of understanding gene function. This is an excellent opportunity for an experienced scientist that desires to make meaningful contributions in the discovery and validation of new therapeutic targets. You will work closely with other scientists that have a passion for finding novel approaches toward the treatment and prevention of disease.

Responsibilities:

Your responsibilities will include establishing and performing a wide variety of cell-based and molecular biological assays designed to provide insights into gene function. The ideal candidate will also have extensive experience in quantitative protein-based and nucleic acid-based detection systems, be highly organized, and enjoys working in a team environment. You will be expected to:

  • Perform a wide variety of cell-based assays
  • Aid in the creation of experimental protocols and SOPs
  • Maintain detailed experimental records
  • Analyze and communicate experimental results
  • Perform general laboratory duties including the ordering of reagents/supplies
  • Be a team player who enjoys an open environment where you can contribute in highly meaningful and impactful ways

Requirements:

  • B.S in molecular biology, biochemistry or related field with 2+ years of experience in a laboratory setting
  • Hands on experience using and manipulating mammalian tissue culture systems
  • Working knowledge of reporter gene systems, ELISA, AlphaLISA, RT-qPCR, gel electrophoresis
  • Proficient in MS Word, Excel and PowerPoint
  • Experience in advanced cell culture systems (e.g. air-liquid interface) is a plus
  • Previous industry experience is preferred
  • Applicants must have authorization to work in the U.S.

Empirico is a venture-backed, next-generation therapeutics company founded on utilizing huge biological datasets, human genetics and programmable biology to power novel target discovery and development. Empirico’s Precision Insights Platform™ was purpose-built for therapeutic discovery and leverages a world-leading dataset and advanced algorithmic approaches to identify and prioritize therapeutic targets with a high probability of translational success. High priority therapeutic targets are experimentally validated in-house prior to progressing through pre-clinical development with the most optimal therapeutic modality. Empirico is headquartered in San Diego, CA with laboratories in Madison, WI.

To all agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

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Wed May 1

Assistant Scientist – Assay Systems

Location: Madison, WI

Position Description: Empirico, an early-stage biotechnology company, is looking for an assistant scientist with a strong background in performing biomarker assays. This is an excellent opportunity for an experienced scientist that desires to make meaningful contributions in the discovery and validation of new therapeutic targets. You will work closely with other scientists that have a passion for finding novel approaches toward the treatment and prevention of disease.

Responsibilities:

Your responsibilities will include establishing and performing a wide variety of biochemical and molecular biological assays designed to provide insights into gene function in in vitro and cell culture models. The ideal candidate will have extensive experience in both protein-based and nucleic acid-based assay systems, be highly organized, and enjoys working in a team environment. You will be expected to:

  • Perform a wide variety of biomarker assays
  • Aid in the creation of experimental protocols and SOPs
  • Maintain detailed experimental records
  • Analyze and communicate experimental results
  • Perform general laboratory duties including the ordering of reagents/supplies
  • Be a team player who enjoys an open environment where you can contribute in highly meaningful and impactful ways

Requirements:

  • B.S. in molecular biology, biochemistry or related field with 2+ years of experience in a laboratory setting
  • Hands on experience of assay systems including ELISA, AlphaLISA, RT-qPCR, reporter gene systems, Luminex
  • Proficient in MS Word, Excel and Powerpoint
  • Experience in cell culture techniques is a plus
  • Previous industry experience is preferred
  • Applicants must have authorization to work in the U.S.

Empirico is a venture-backed, next-generation therapeutics company founded on utilizing huge biological datasets, human genetics and programmable biology to power novel target discovery and development. Empirico’s Precision Insights Platform™ was purpose-built for therapeutic discovery and leverages a world-leading dataset and advanced algorithmic approaches to identify and prioritize therapeutic targets with a high probability of translational success. High priority therapeutic targets are experimentally validated in-house prior to progressing through pre-clinical development with the most optimal therapeutic modality. Empirico is headquartered in San Diego, CA with laboratories in Madison, WI.

To all agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

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Wed May 1

Scientist / Sr. Scientist – Translational Genetics

Location:  San Diego, CA

Position Description: Empirico, an early-stage biotechnology company, is looking for a scientist-level computational geneticist experienced in analyzing and interpreting large scale human genetics data for the purpose of therapeutic target discovery. This is an excellent opportunity for a highly-motivated, creative scientist to be a vital member of a team of experts dedicated to identifying new disease targets and translating those insights into therapeutic programs.

Responsibilities:

Your responsibilities will include using human genetics data to identify new therapeutic targets in order to advance Empirico’s drug discovery and development pipeline. You will be expected to:

  • Work with a multidisciplinary team consisting of human geneticists, bioinformaticians and software engineers to lead the design, execution, and interpretation of in silico human genetic studies
  • Discover novel genetic associations with human diseases using Empirico’s world-leading target discovery platform
  • Provide genetic intelligence on therapeutic targets of interest for external collaborators
  • Create and deliver expert-level presentations that clearly communicate genetic discoveries and stories to colleagues, collaborators and investors
  • Translate findings from genetic studies into therapeutic hypotheses and contribute to decisions around therapeutic modality and targeting strategies
  • Collaborate with biologists and chemists on the design of in vitro and in vivo experiments to validate therapeutic hypotheses that are motivated by human genetics findings
  • Provide novel ideas and critical thinking for the continued development and improvement of Empirico’s target discovery platform
  • Survey the latest developments in the broader genetics community and incorporate relevant approaches and findings into internal studies

Requirements:

  • This position requires an MD or PhD with 0-3 years of postgraduate experience in human genetics research with a translational focus. Recent graduates and postdocs encouraged to apply.
  • Core background MUST be in computational genetics; this position is NOT for scientists with a primarily wet-lab background
  • A firm understanding of the principles of statistical genetics and genetic epidemiology
  • Demonstrated ability to design, lead and interpret human genetics studies and to discern therapeutic hypotheses
  • Familiarity with the design of functional studies to understand the mechanistic basis for genetic associations
  • Applicants must have authorization to work in the U.S.

Empirico is a venture-backed, next-generation therapeutics company founded on utilizing huge biological datasets, human genetics and programmable biology to power novel target discovery and development. Empirico’s Precision Insights Platform™ was purpose-built for therapeutic discovery and leverages a world-leading dataset and advanced algorithmic approaches to identify and prioritize therapeutic targets with a high probability of translational success. High priority therapeutic targets are experimentally validated in-house prior to progressing through pre-clinical development with the most optimal therapeutic modality. Empirico is headquartered in San Diego, CA with laboratories in Madison, WI.

To all agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

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Fri Apr 12

Associate Director / Director – Translational Genetics

Location:  San Diego, CA

Position Description: Empirico, an early-stage biotechnology company, is looking for a director-level computational geneticist experienced in analyzing and interpreting large scale human genetics data for the purpose of therapeutic target discovery. This is an excellent opportunity for a highly-motivated, creative scientist to be a vital member of a team of experts dedicated to identifying new disease targets and translating those insights into therapeutic programs.

Responsibilities:

Your responsibilities will include using human genetics data to identify new therapeutic targets in order to advance Empirico’s drug discovery and development pipeline. You will be expected to:

  • Work with a multidisciplinary team consisting of human geneticists, bioinformaticians and software engineers to lead the design, execution, and interpretation of in silico human genetic studies
  • Discover novel genetic associations with human diseases using Empirico’s world-leading target discovery platform
  • Provide genetic intelligence on therapeutic targets of interest for external collaborators
  • Create and deliver expert-level presentations that clearly communicate genetic discoveries and stories to colleagues, collaborators and investors
  • Translate findings from genetic studies into therapeutic hypotheses and contribute to decisions around therapeutic modality and targeting strategies
  • Collaborate with biologists and chemists on the design of in vitro and in vivo experiments to validate therapeutic hypotheses that are motivated by human genetics findings
  • Provide novel ideas and critical thinking for the continued development and improvement of Empirico’s target discovery platform
  • Survey the latest developments in the broader genetics community and incorporate relevant approaches and findings into internal studies

Requirements:

  • This position requires an MD or PhD with at least 4-6 years of postgraduate experience in human genetics research with a translational focus. Pay and title commensurate with experience
  • Core background MUST be in computational genetics; this position is NOT for scientists with a primarily wet-lab background
  • A firm understanding of the principles of statistical genetics and genetic epidemiology
  • Demonstrated ability to design, lead and interpret human genetics studies and to discern therapeutic hypotheses
  • Familiarity with the design of functional studies to understand the mechanistic basis for genetic associations
  • Applicants must have authorization to work in the U.S.

Empirico is a venture-backed, next-generation therapeutics company founded on utilizing huge biological datasets, human genetics and programmable biology to power novel target discovery and development. Empirico’s Precision Insights Platform™ was purpose-built for therapeutic discovery and leverages a world-leading dataset and advanced algorithmic approaches to identify and prioritize therapeutic targets with a high probability of translational success. High priority therapeutic targets are experimentally validated in-house prior to progressing through pre-clinical development with the most optimal therapeutic modality. Empirico is headquartered in San Diego, CA with laboratories in Madison, WI.

To all agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Continue reading